Effects of ketamine on brain function during smooth pursuit eye movements
نویسندگان
چکیده
منابع مشابه
Effects of ketamine on brain function during smooth pursuit eye movements.
The uncompetitive NMDA receptor antagonist ketamine has been proposed to model symptoms of psychosis. Smooth pursuit eye movements (SPEM) are an established biomarker of schizophrenia. SPEM performance has been shown to be impaired in the schizophrenia spectrum and during ketamine administration in healthy volunteers. However, the neural mechanisms mediating SPEM impairments during ketamine adm...
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A potential application of studying eye movements with functional MRI (fMRI) is to examine patient populations with known eye movement dysfunction, but the reliability with which normal subjects demonstrate activity in specific brain regions has not been established. To date, fMRI studies of smooth-pursuit eye movements have used relatively small numbers of subjects and have been restricted to ...
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Segregating a moving object from its visual context is particularly relevant for the control of smooth-pursuit eye movements. We examined the interaction between a moving object and a stationary or moving visual context to determine the role of the context motion signal in driving pursuit. Eye movements were recorded from human observers to a medium-contrast Gaussian dot that moved horizontally...
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With accurate measurement of eye position during smooth tracking, comparison of the retinal and perceived paths of spots of light moving in harmonic motion indicates little compensation for smooth pursuit eye movements by the perceptual system. The data suggest that during smooth pursuit. the perceptual system has access to information about direction of tracking. and assumes a relatively low s...
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ژورنال
عنوان ژورنال: Human Brain Mapping
سال: 2016
ISSN: 1065-9471
DOI: 10.1002/hbm.23294